Biomarkers in diabetes: hemoglobin A1c, vascular and tissue markers
نویسندگان
چکیده
منابع مشابه
Hemoglobin A1c in Diabetes: Panacea or Pointless?
Glycation is the nonenzymatic attachment of a monosaccharide to amino groups of proteins. The reaction has been recognized for many years in the food industry, where it is known as browning (also termed the Maillard reaction) and is responsible for the formation of commonly ingested items, such as toast. In patients with diabetes, glucose accumulation results in enhanced glycation of many prote...
متن کاملGlycated hemoglobin A1C and diabetes mellitus in critically ill patients
BACKGROUND Hyperglycemia has been detected in many critically ill patients in the department of emergency medicine. But its mechanism and prognosis have not been well elucidated. In this study, we measured the serum level of glycated hemoglobin A1C (HbA1c) in critically ill patients to evaluate the effects of hyperglycemia on the prognosis of the patients. METHODS A total of 826 critically il...
متن کاملHemoglobin A1c: Clinical applications and analytical considerations
Diabetes Mellitus (DM) is the most common disorder of carbohydrate metabolism. Hyperglycemia is the common feature of DM. Hyperglycemia causes cardiovascular, renal, ocular, and peripheral nerve disorders in patients with diabetes. Glycemic regulation plays an essential role in controlling these complications. Thus, evaluation of the glycemic control status is crucial in the management of DM. H...
متن کاملRed cell transfusion decreases hemoglobin A1c in patients with diabetes.
Hemoglobin A1c (Hb A1c) 1 is a mainstay of diabetes diagnosis and management that allows clinicians to estimate the recent mean blood glucose concentration of a patient. Glycation of hemoglobin is an irreversible, nonenzymatic process that depends on the glucose concentration in red blood cells (RBCs), and Hb A1c represents the integrated glucose concentration in RBCs over their life span. RBC ...
متن کاملShort Communication Glycated Hemoglobin “A1c” and Diabetes Complications
Objectives: This study aimed to highlight the association of HbA1c with diabetic related complications. Material and Methods: This retrospective study has been conducted in endocrinology department of Alnoor Specialist Hospital, Makkah, Saudi Arabia, from January 2007 to December 2009. Data has been collected from diabetic patients’ files that were referred to the diabetes outpatient department...
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ژورنال
عنوان ژورنال: Translational Research
سال: 2012
ISSN: 1931-5244
DOI: 10.1016/j.trsl.2012.01.009